"The Prince of Darkness, otherwise known as Ozzy Osbourne, has ordered scientists to sequence his genome. Heavy metal howler Ozzy Osbourne decided to have his DNA sequenced and analyzed to solve a mystery. The British heavy metal icon, who became famous as much for his prodigious drug and alcohol abuse also as his music, said having his genome sequenced could offer clues about why he’s still alive. Osborne appeared at TEDMED 2010 in San Diego today to present the findings.
Why had been the genome from Ozzy being sequenced
Missouri bioscience firm Cofactor Genomics was responsible for Ozzy Osbour's genome getting sequenced. Knome Inc. then was able to analyze it. CNN had been able to speak to Jorge Conde of Knome. He said that because Osbourne had been diagnosed with a disease similar to Parkinson's, he wanted to know more about his ancestry. However, Osbourne had a more characteristic explanation. In an Oct. 24 guest column for the Sun Times, Osbourne said “Given the swimming pools of booze I’ve guzzled over the years — not to mention all of the cocaine, morphine, sleeping pills, cough syrup, LSD, Rohypnol … you name it – there’s really no plausible medical reason why I should still be alive. Possibly my DNA could say why.”
Now we know the Neanderthal is in Ozzy
The genome of Osbourne taught him something about his ancestry. As outlined by Scientific American, Osbourn's 10th chromosome has "a little segment" of something there. This implies that a Neanderthal was in Osbourne's distant ancestry. It would are seriously shocking to discover someone had a Neanderthal DNA in their genome, except possibly in Osbourne. 1 to 4 percent of those not from Africa have Neanderthals in their DNA as had been discovered this year. Learning about being a Neanderthal made Osbourne feel "tickled".
Ozzy wins the genetic lottery
Osbourne’s ability to emerge from years of substance abuse alive could possibly be tied to a gene in his DNA sequence that makes a protein radically different than that produced by most people. Osbourne also has an unusual variant near one of the alcohol dehydrogenase genes involved with metabolizing alcohol that may explain why his body has kept up more than would be expected in other people. This had been all explained by a Knome Scientist. He said, “He’s a 61-year-old healthy guy, and that speaks for itself. That suggests he’s done OK within the genetic lottery.”
Sources
CNN
news.blogs.cnn.com/2010/10/29/fridays-intriguing-people-31/?npt=NP1
Scientific American
scientificamerican.com/article.cfm?id=ozzy-osbourne-genome&page=2
The Sunday Times
thesundaytimes.co.uk/sto/
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